KMID : 0360220130540091435
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Journal of the Korean Ophthalmological Society 2013 Volume.54 No. 9 p.1435 ~ p.1439
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Confocal Microscopic Findings of Corneal Tissue in Fuchs¡¯ Corneal Endothelial Dystrophy
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Park Young-Min
Choi Beom-Seok Lee Jong-Soo
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Abstract
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Purpose: To analyze the morphology and density of corneal tissue in patients with early stage Fuchs¡¯ corneal endothelial dystrophy (FCED) by in vivo confocal microscopy (IVCM).
Case summary: Each layer of the cornea in 2 patients with early-stage FCED was examined with IVCM (ConfoScan 4.0, NIDEK, Co. Ltd., albignasego, Italy). Cross-sectioned corneal images of the corneal epithelium, Bowman¡¯s layer, stromal layer, Descemet¡¯s membrane, and endothelium were evaluated. Corneal epithelium, Bowman¡¯s layer, and anterior stroma of both patients showed no abnormalities. Case 1 was diagnosed as Stage 1 FCED, demonstrating typical changes including pleomorphism, polymegathism, and the presence of guttae in the corneal endothelial layer. Case 2 was diagnosed as Stage 2 FCED, showing several hyper-reflective whitish dots in the posterior stroma, hypo-reflective vertical strands in the stroma adjacent to Descemet¡¯s membrane, and pleomorphism, polymegathism, and guttae in the corneal endothelial layer.
Conclusions: IVCM is a non-invasive and effective tool to diagnose early-stage FCED.
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KEYWORD
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Confocal microscopy, Fuchs¡¯ corneal endothelial dystrophy
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